SCHEMBL6953255

SCHEMBL6953255

CCOC(Cc1ccc(C(=O)CCN2CN(C)c3cc(C)ccc3C2=O)cc1)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 16/20 0.43
PPARG P37231 13/20 0.43
PPARD Q03181 5/20 0.43
HSD11B1 P28845 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6957206 0.95 PPARA (0.42) PPARAPPARGPPARD
SCHEMBL6952116 0.79 DRD2 (0.36) PPARAPPARGPPARDHSD11B1
SCHEMBL6951661 0.74 PPARA (0.41) PPARAPPARGPPARD
SCHEMBL6956751 0.71 PPARA (0.43) PPARAPPARGPPARD
SCHEMBL17680422 0.70 PPARA (0.68) PPARAPPARGPPARD
SCHEMBL6955247 0.64 MAPT (0.44) PPARAPPARGPPARD
SCHEMBL6945038 0.63 PPARA (0.35) PPARAPPARGPPARD
SCHEMBL6738097 0.63 PPARA (0.77) PPARAPPARGPPARD
SCHEMBL6731909 0.63 PPARA (0.77) PPARAPPARGPPARD
SCHEMBL5543269 0.63 PPARA (0.72) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0903343-B1 Alpha-Substituted phenylpropionic acid derivative and medicine containing the same SSP CO LTD (JP) 2003-05-28 EP disclosed
EP-0903343-A1 Alpha-Substituted phenylpropionic acid derivative and medicine containing the same SSP Co., Ltd. (JP) 1999-03-24 EP disclosed