Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | CYP2J2 | P51589 | 3/20 | 0.31 |
| ▸ | TPH1 | P17752 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6953255 | 0.79 | PPARA (0.43) | HSD11B1PPARGPPARDPPARA | |
| SCHEMBL6952423 | 0.77 | PPARG (0.34) | ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL6948070 | 0.65 | TP53 (0.35) | ALDH1A1LMNAMAPTKMT2APPARG | |
| SCHEMBL6951661 | 0.61 | PPARA (0.41) | PPARGPPARDPPARA | |
| SCHEMBL24798048 | 0.58 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL2762921 | 0.56 | THRA (0.45) | S1PR5LMNAMAPTCYP2J2 | |
| SCHEMBL28342825 | 0.55 | KMT2A (0.55) | MAPTKMT2A | |
| SCHEMBL9419411 | 0.55 | KMT2A (0.69) | ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL918486 | 0.55 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL10767977 | 0.54 | ALDH1A1 (0.55) | DRD4DRD3ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |