Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 20/20 | 0.63 |
| ▸ | DRD3 | P35462 | 7/20 | 0.62 |
| ▸ | DRD2 | P14416 | 6/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955611 | 0.87 | DRD2 (0.73) | DRD4DRD3DRD2 | |
| SCHEMBL11243700 | 0.85 | DRD2 (0.63) | DRD4DRD3DRD2 | |
| SCHEMBL11237343 | 0.85 | DRD2 (0.63) | DRD4DRD3DRD2 | |
| SCHEMBL11230823 | 0.84 | DRD2 (0.62) | DRD4DRD3DRD2 | |
| SCHEMBL11230827 | 0.84 | DRD2 (0.62) | DRD4DRD3DRD2 | |
| SCHEMBL9021909 | 0.84 | HTR4 (0.72) | DRD4 | |
| SCHEMBL9021444 | 0.82 | HTR4 (0.66) | DRD4DRD2 | |
| SCHEMBL7296558 | 0.82 | HTR4 (0.60) | DRD4 | |
| SCHEMBL11242259 | 0.78 | DRD2 (0.54) | DRD4DRD3DRD2 | |
| SCHEMBL11243730 | 0.78 | DRD2 (0.54) | DRD4DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550550-B1 | 3,9-DIAZABICYCLO (3.3.1) NONAN-7-YL DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 2003-07-16 | — | — | EP | disclosed |
| EP-0550550-A1 | 3,9-DIAZABICYCLO (3.3.1) NONAN-7-YL DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Beecham Group p.l.c. (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992005174-A1 | 3,9-DIAZABICYCLO (3.3.1) NONAN-7-YL DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1992-04-02 | — | — | WO | disclosed |