Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | KYNU | Q16719 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954031 | 1.00 | MEN1 (0.48) | MEN1KMT2ALMNAALDH1A1CYP3A4 | |
| SCHEMBL4026193 | 0.90 | MEN1 (0.57) | MEN1KMT2ACTSLCTSBCTSS | |
| SCHEMBL4026197 | 0.90 | MEN1 (0.57) | MEN1KMT2ACTSLCTSBCTSS | |
| SCHEMBL4023412 | 0.90 | MEN1 (0.48) | MEN1KMT2ALMNAALDH1A1CYP3A4 | |
| Dicyclohexylcarbodiimide SCHEMBL7331282 | 0.89 | CTSL (0.43) | MEN1KMT2ALMNAALDH1A1CYP3A4 | |
| SCHEMBL4021266 | 0.88 | MEN1 (0.49) | MEN1KMT2ALMNAALDH1A1CYP3A4 | |
| SCHEMBL8183267 | 0.87 | CTSL (0.40) | MEN1KMT2AALDH1A1CTSLCTSB | |
| SCHEMBL8183264 | 0.87 | CTSL (0.40) | MEN1KMT2AALDH1A1CTSLCTSB | |
| SCHEMBL4022442 | 0.85 | MEN1 (0.61) | MEN1KMT2ALMNAALDH1A1CYP3A4 | |
| SCHEMBL4022774 | 0.85 | MEN1 (0.61) | MEN1KMT2ALMNAALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738150-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6117866-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-09-12 | — | — | US | disclosed |