Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | KYNU | Q16719 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8183267 | 1.00 | CTSL (0.40) | CTSLCTSBCTSSCTSKKYNU | |
| SCHEMBL6954036 | 0.87 | MEN1 (0.48) | CTSLCTSBCTSSCTSKKYNU | |
| SCHEMBL6954031 | 0.87 | MEN1 (0.48) | CTSLCTSBCTSSCTSKKYNU | |
| SCHEMBL8327721 | 0.83 | CYP3A4 (0.43) | CTSLCTSBALDH1A1 | |
| SCHEMBL12604584 | 0.81 | SYK (0.42) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4027455 | 0.80 | LPAR1 (0.43) | CTSLCTSBCTSSCTSKKYNU | |
| SCHEMBL4027452 | 0.80 | LPAR1 (0.43) | CTSLCTSBCTSSCTSKKYNU | |
| SCHEMBL6954041 | 0.79 | CASP1 (0.44) | — | |
| SCHEMBL6954029 | 0.79 | CASP1 (0.44) | — | |
| SCHEMBL8178607 | 0.79 | LPAR1 (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6159964-A | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-12-12 | — | — | US | disclosed |
| EP-0906103-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-04-07 | — | — | EP | disclosed |
| EP-0906103-A4 | — | — | 1999-04-07 | — | — | EP | disclosed |
| WO-1997024124-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |