Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 5/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.55 |
| ▸ | POLH | Q9Y253 | 5/20 | 0.55 |
| ▸ | MAOA | P21397 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.55 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957856 | 0.84 | AR (0.56) | MEN1KMT2ACYP3A4MAPTALDH1A1 | |
| SCHEMBL22738310 | 0.79 | MEN1 (0.75) | MEN1KMT2ACYP3A4MAPTALDH1A1 | |
| SCHEMBL6961122 | 0.78 | HPGD (0.57) | MEN1KMT2ACYP3A4MAPTALDH1A1 | |
| SCHEMBL14134581 | 0.75 | MEN1 (0.69) | MEN1KMT2ACYP3A4MAPTALDH1A1 | |
| SCHEMBL32679657 | 0.73 | MEN1 (0.82) | MEN1KMT2ACYP3A4MAPTALDH1A1 | |
| Tricetin SCHEMBL158384 | 0.71 | MEN1 (1.00) | MEN1KMT2ACYP3A4MAPTALDH1A1 | |
| Apigenin SCHEMBL19428 | 0.71 | KMT2A (1.00) | MEN1KMT2ACYP3A4MAPTALDH1A1 | |
| Apigenin SCHEMBL29351464 | 0.71 | KMT2A (1.00) | MEN1KMT2ACYP3A4MAPTALDH1A1 | |
| SCHEMBL14464104 | 0.71 | BACE1 (0.77) | MEN1KMT2ACYP3A4MAPTALDH1A1 | |
| SCHEMBL29424233 | 0.71 | BACE1 (0.77) | MEN1KMT2ACYP3A4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711762-B1 | PROCESS FOR PRODUCING TETRAZOLE COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2003-08-06 | — | — | EP | disclosed |
| US-6277998-B1 | REACTING 2-CYANO-4-OXO-4H-BENZOPYRAN COMPOUND WITH HYDROGEN SULFIDE AND THEN REACTING PROUDCT WITH ALKYL HALIDE; REACTING THE PRODUCT WITH HYDRAZINE OR ITS SALT AND THEN WITH NITROUS ACID COMPOUND TO OBTAIN TETRAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-08-21 | — | — | US | disclosed |
| US-6191289-B1 | REACTING A 4-OXO-4H-BENZOPYRAN GROUP SUBSTITUTED WITH AMIDE OR A PHENYL GROUP IN ITS 2 POSITION IS REACTED WITH ANHYDROUS HYDRAZINE OR SALT IN PRESENCE OF CATALYST FOLLOWED BY REACTING WITH NITROUS ACID OR SALT TO FORM TETRAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-02-20 | — | — | US | disclosed |
| US-5874593-A | SULFUR CONTAINING AMIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |
| EP-0711762-A1 | PROCESS FOR PRODUCING TETRAZOLE COMPOUND AND INTERMEDIATE THEREFOR | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |