Apigenin

Apigenin

SCHEMBL29351464

O=c1cc(-c2ccc(O)cc2)oc2cc(O)cc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 1.00
CYP1B1 Q16678 7/20 1.00
ABCB1 P08183 6/20 1.00
MEN1 O00255 6/20 1.00
CYP3A4 P08684 6/20 1.00
MAPT P10636 6/20 1.00
CYP1A1 P04798 6/20 1.00
ALDH1A1 P00352 5/20 1.00
HPGD P15428 5/20 1.00
FTO Q9C0B1 5/20 1.00
CYP1A2 P05177 5/20 1.00
POLH Q9Y253 5/20 1.00
IP6K2 Q9UHH9 5/20 1.00
TP53 P04637 4/20 1.00
CYP2D6 P10635 4/20 1.00
CYP2C9 P11712 4/20 1.00
MAOA P21397 4/20 1.00
MAOB P27338 4/20 1.00
CYP2C19 P33261 4/20 1.00
SMN1; SMN2 Q16637 4/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Apigenin SCHEMBL19428 1.00 KMT2A (1.00) KMT2ACYP1B1ABCB1MEN1CYP3A4
Apigenin SCHEMBL5083245 1.00 KMT2A (1.00) KMT2ACYP1B1ABCB1MEN1CYP3A4
Apigenin SCHEMBL30544810 0.98 KMT2A (0.97) KMT2ACYP1B1ABCB1MEN1CYP3A4
Apigenin SCHEMBL29448148 0.98 KMT2A (0.97) KMT2ACYP1B1ABCB1MEN1CYP3A4
Apigenin SCHEMBL29968480 0.98 KMT2A (0.97) KMT2ACYP1B1ABCB1MEN1CYP3A4
Apigenin SCHEMBL1658882 0.98 KMT2A (0.97) KMT2ACYP1B1ABCB1MEN1CYP3A4
Apigenin SCHEMBL31168790 0.98 KMT2A (0.97) KMT2ACYP1B1ABCB1MEN1CYP3A4
Apigenin SCHEMBL31477961 0.98 KMT2A (0.97) KMT2ACYP1B1ABCB1MEN1CYP3A4
Apigenin SCHEMBL29872582 0.98 KMT2A (0.97) KMT2ACYP1B1ABCB1MEN1CYP3A4
Apigenin SCHEMBL29458838 0.98 KMT2A (0.97) KMT2ACYP1B1ABCB1MEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 315 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN claimed
EP-3699174-B1 COMPOSITION FOR PREVENTING OR TREATING TNF-RELATED DISEASES, CONTAINING DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR INHIBITING TNF ACTIVITY BY USING SAME ILAB (KR) 2025-11-12 EP claimed
WO-2025229086-A1 ADHESIVE COSMETIC COMPOUNDS AND USES THEREOF SKINOSIVE (FR) 2025-11-06 WO claimed
EP-4622640-A1 COMPOSITIONS AND METHODS FOR MODULATING SLEEP AND USES THEREOF Brightseed, Inc. (US) 2025-10-01 EP claimed
CN-118973616-A Trkb ligand conjugated compounds and uses thereof 阿达尔克斯制药有限公司 2024-11-15 CN claimed
WO-2024112947-A1 COMPOSITIONS AND METHODS FOR MODULATING SLEEP AND USES THEREOF BRIGHTSEED, INC. (US) 2024-05-30 WO claimed
CN-117298222-A Dendrobium officinale leaf polyphenol extract, preparation method thereof and application thereof in preparation of products for preventing or treating chronic colitis 浙江工业大学 2023-12-29 CN claimed
CN-116519827-A Method for inhibiting sesame pathogenic bacteria active ingredient generated by analyzing penicillium beijerinckii based on non-target metabonomics 河南省农业科学院植物保护研究所 2023-08-01 CN claimed
EP-3982924-B1 PLANT EXTRACT MIXTURE FOR USE IN THE PREVENTION AND/OR TREATMENT OF CHRONIC INFLAMMATORY BOWEL DISEASES VALBIOTIS (FR) 2023-07-26 EP claimed
CN-115710592-B Preparation process of 4',5, 7-trihydroxy flavanone 成都欧康医药股份有限公司 2023-05-26 CN claimed
CN-115969838-A Application of natural composition as estrogen receptor degradation agent 三峡大学 2023-04-18 CN claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2022122968-A1 COMPOUNDS FOR USE IN THE TREATMENT OF COVID-19 DOMPE' FARMACEUTICI SPA (IT) 2022-06-16 WO claimed
EP-3533454-B1 COMPOSITION COMPRISING A MIXTURE OF PLANT EXTRACTS OR A MIXTURE OF MOLECULES CONTAINED IN SAID PLANTS AND USE TO ACT ON THE CARBOHYDRATE AND/OR LIPID METABOLISM VALBIOTIS (FR) 2022-04-20 EP claimed
CN-112514710-B Arbuscular mycorrhizal fungi continuous type propagation incubator 山西农业大学 2022-03-22 CN claimed
CN-113956226-A Method for synthesizing carvachin 南京科技职业学院 2022-01-21 CN claimed
EP-4103144-B1 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2026-05-27 EP disclosed
CN-113956226-A Method for synthesizing carvachin 南京科技职业学院 2022-01-21 CN disclosed