Apigenin

Apigenin

SCHEMBL19428

O=c1cc(-c2ccc(O)cc2)oc2cc(O)cc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 1.00
CYP1B1 Q16678 7/20 1.00
ABCB1 P08183 6/20 1.00
MEN1 O00255 6/20 1.00
CYP3A4 P08684 6/20 1.00
MAPT P10636 6/20 1.00
CYP1A1 P04798 6/20 1.00
ALDH1A1 P00352 5/20 1.00
HPGD P15428 5/20 1.00
FTO Q9C0B1 5/20 1.00
CYP1A2 P05177 5/20 1.00
POLH Q9Y253 5/20 1.00
IP6K2 Q9UHH9 5/20 1.00
TP53 P04637 4/20 1.00
CYP2D6 P10635 4/20 1.00
CYP2C9 P11712 4/20 1.00
MAOA P21397 4/20 1.00
MAOB P27338 4/20 1.00
CYP2C19 P33261 4/20 1.00
SMN1; SMN2 Q16637 4/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Apigenin SCHEMBL29351464 1.00 KMT2A (1.00) KMT2ACYP1B1ABCB1MEN1CYP3A4
Apigenin SCHEMBL5083245 1.00 KMT2A (1.00) KMT2ACYP1B1ABCB1MEN1CYP3A4
Apigenin SCHEMBL30544810 0.98 KMT2A (0.97) KMT2ACYP1B1ABCB1MEN1CYP3A4
Apigenin SCHEMBL29448148 0.98 KMT2A (0.97) KMT2ACYP1B1ABCB1MEN1CYP3A4
Apigenin SCHEMBL29968480 0.98 KMT2A (0.97) KMT2ACYP1B1ABCB1MEN1CYP3A4
Apigenin SCHEMBL1658882 0.98 KMT2A (0.97) KMT2ACYP1B1ABCB1MEN1CYP3A4
Apigenin SCHEMBL31168790 0.98 KMT2A (0.97) KMT2ACYP1B1ABCB1MEN1CYP3A4
Apigenin SCHEMBL31477961 0.98 KMT2A (0.97) KMT2ACYP1B1ABCB1MEN1CYP3A4
Apigenin SCHEMBL29872582 0.98 KMT2A (0.97) KMT2ACYP1B1ABCB1MEN1CYP3A4
Apigenin SCHEMBL29458838 0.98 KMT2A (0.97) KMT2ACYP1B1ABCB1MEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 27711 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848462-B1 BAICALEIN- AND SCUTELLAREIN-SYNTHESIZING MICROORGANISM, PREPARATION METHOD, AND APPLICATIONS THEREOF CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2026-05-27 EP claimed
CN-122084804-A Method for detecting contents of multi-index components of cough syrup oral liquid 2026-05-26 CN claimed
CN-122075438-A Synergistic anticancer application of redox responsive coacervate delivery chrysin and 3-methyladenine 2026-05-26 CN claimed
CN-122075559-A Portulaca oleracea extract based on bioaffinity ultrafiltration screening and preparation method and application thereof 2026-05-26 CN claimed
CN-122070916-A Application of arteannuin with double functions in promoting liver cell maturation and relieving liver lipid metabolism dysfunction 广州市第一人民医院(广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院) 2026-05-22 CN claimed
WO-2026107510-A1 HOT-MELT ADHESIVE COMPOSITION AND METHOD OF APPLICATION BIOBOND ADHESIVES, INC. (US) 2026-05-21 WO claimed
EP-4743070-A1 NOVEL INHIBITORS OF THYMIC STROMAL LYMPHOPOIETIN Symrise AG (DE) 2026-05-20 EP claimed
EP-4744663-A2 SKIN COMPOSITION Eaderm Co., Ltd. (JP) 2026-05-20 EP claimed
CN-122056926-A Probiotic composition containing melatonin and application of composition in sleep 南京北极光生物科技有限公司 2026-05-19 CN claimed
CN-122056867-A Citrus flavonoid compound and application thereof in treating acute lung injury 华中农业大学 2026-05-19 CN claimed
EP-0330240-A1 Camomile drug and its use in the preparation of camomile extracts, camomile oil and pharmaceutical agents ROBUGEN GMBH PHARMAZEUTISCHE FABRIK (DE) 1989-08-30 EP claimed
EP-0290442-A1 PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS CHEMEX PHARMACEUTICALS, INC. (US) 1988-11-17 EP claimed
US-4774229-A ANTITUMOR AGENTS, SKIN DISORDERS, CANCER TREATMENT CHEMEX PHARMACEUTICALS, INC. (US) 1988-09-27 US claimed
WO-1988003805-A1 PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS CHEMEX PHARMACEUTICALS, INC. (US) 1988-06-02 WO claimed
EP-0245931-A2 Nodulation inducing factors LUBRIZOL GENETICS INC. (US) 1987-11-19 EP claimed
WO-1987006833-A1 MODIFICATION OF PLANT EXTRACTS FROM ZYGOPHYLLACEAE CHEMEX PHARMACEUTICALS, INC. (US) 1987-11-19 WO claimed
US-4617293-A Flavonoid phosphate salts of aminoglycoside antibiotics MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1986-10-14 US claimed
EP-0052086-B1 PROCESS FOR PRODUCING FLAVONE DERIVATIVES WITH MEDICINAL ACTIVITY BONOMELLI S.p.A. (IT) 1986-01-29 EP claimed
EP-0052086-A1 Process for producing flavone derivatives with medicinal activity BONOMELLI S.p.A. (IT) 1982-05-19 EP claimed
US-4313880-A Extractive process for preparing apigenin BENOMELLI S.P.A. (IT) 1982-02-02 US claimed