Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.45 |
| ▸ | HTR2A | P28223 | 8/20 | 0.45 |
| ▸ | HTR2C | P28335 | 8/20 | 0.45 |
| ▸ | HTR2B | P41595 | 8/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954300 | 1.00 | SIGMAR1 (0.45) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL6968686 | 0.92 | SIGMAR1 (0.45) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL6968684 | 0.92 | SIGMAR1 (0.45) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL6965541 | 0.79 | NAAA (0.42) | — | |
| SCHEMBL6963804 | 0.79 | SIGMAR1 (0.41) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL6958774 | 0.77 | TACR1 (0.36) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL6846766 | 0.77 | CHRM3 (0.33) | — | |
| SCHEMBL6852753 | 0.77 | CHRM3 (0.33) | — | |
| SCHEMBL6957860 | 0.77 | CNR1 (0.35) | HTR2AHTR2CHTR2BALOX5 | |
| SCHEMBL6957912 | 0.77 | HTR2A (0.35) | SIGMAR1HTR2AHTR2CHTR2BOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610721-B2 | Imidazo heterocyclic compounds | NOVO NORDISK A/S (DK) | 2003-08-26 | — | — | US | disclosed |
| EP-1268483-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2003-01-02 | — | — | EP | disclosed |
| US-20010049385-A1 | Imidazo heterocyclic compounds | HIGH POINT PHARMACEUTICALS, LLC | 2001-12-06 | — | — | US | disclosed |
| WO-2001068651-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2001-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010049385-A1 | Imidazo heterocyclic compounds | HRH4, HRH3, HRH2 | SIGMAR1 269/4885HTR2A 104/4885HTR2C 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.