Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.41 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.41 |
| ▸ | SOD1 | P00441 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954390 | 1.00 | TBXAS1 (0.56) | TBXAS1CYP19A1POLBCYP24A1CYP11B1 | |
| SCHEMBL6955623 | 0.86 | CYP19A1 (0.52) | TBXAS1CYP19A1POLBCYP24A1CYP11B1 | |
| SCHEMBL6955615 | 0.86 | CYP19A1 (0.52) | TBXAS1CYP19A1POLBCYP24A1CYP11B1 | |
| SCHEMBL6963677 | 0.85 | CYP19A1 (0.60) | TBXAS1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6963682 | 0.85 | CYP19A1 (0.60) | TBXAS1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8347428 | 0.82 | TBXAS1 (0.68) | TBXAS1CYP19A1POLBCYP24A1CYP11B1 | |
| SCHEMBL8347430 | 0.82 | TBXAS1 (0.68) | TBXAS1CYP19A1POLBCYP24A1CYP11B1 | |
| Hydrochloric Acid SCHEMBL28253387 | 0.80 | TBXAS1 (0.69) | TBXAS1CYP19A1POLBCYP24A1CYP11B1 | |
| SCHEMBL11156491 | 0.79 | TBXAS1 (0.61) | TBXAS1CYP19A1POLBCYP11B1CYP11B2 | |
| SCHEMBL6959069 | 0.79 | LMNA (0.45) | TBXAS1CYP19A1POLBRELACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974584-B1 | FUSED RING COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-01-15 | — | — | EP | claimed |
| US-6420375-B1 | ANTITUMOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-16 | — | — | US | claimed |
| EP-0974584-A1 | FUSED RING COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-01-26 | — | — | EP | claimed |
| JP-10291981-A | — | — | None | — | — | JP | disclosed |
| EP-0974584-B1 | FUSED RING COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-6420375-B1 | ANTITUMOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-0974584-A1 | FUSED RING COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-01-26 | — | — | EP | disclosed |
| JP-H10291981-A | CONDENSED RING COMPOUND, ITS PRODUCTION AND USE | TAKEDA CHEM IND LTD | 1998-11-04 | — | — | JP | disclosed |