Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.32 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | MARK3 | P27448 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PTGFR | P43088 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954489 | 1.00 | PIK3CD (0.33) | PIK3CDPIK3C2BMTORKCNH3KMT2A | |
| Hydrochloric Acid SCHEMBL6961955 | 0.99 | KCNH3 (0.34) | PIK3CDPIK3C2BMTORKCNH3KMT2A | |
| Hydrochloric Acid SCHEMBL6961952 | 0.99 | KCNH3 (0.34) | PIK3CDPIK3C2BMTORKCNH3KMT2A | |
| SCHEMBL6967941 | 0.92 | TRPC3 (0.34) | KCNH3KMT2AMEN1JAK2JAK1 | |
| SCHEMBL6967711 | 0.89 | TRPC3 (0.37) | KCNH3KMT2AMEN1JAK2JAK1 | |
| SCHEMBL6967978 | 0.89 | PIK3CD (0.36) | PIK3CDPIK3C2BKCNH3JAK2JAK1 | |
| SCHEMBL6963858 | 0.89 | PIK3CD (0.36) | PIK3CDPIK3C2BKCNH3JAK2JAK1 | |
| Hydrochloric Acid SCHEMBL6968345 | 0.89 | KCNH3 (0.33) | KCNH3KMT2AMEN1XIAPJAK2 | |
| Hydrochloric Acid SCHEMBL6968349 | 0.89 | KCNH3 (0.33) | KCNH3KMT2AMEN1XIAPJAK2 | |
| Hydrochloric Acid SCHEMBL6956268 | 0.88 | PIK3CD (0.36) | PIK3CDPIK3C2BKCNH3JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | claimed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | claimed |