Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | MC1R | Q01726 | 1/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | MARK3 | P27448 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963858 | 1.00 | PIK3CD (0.36) | PIK3CDPIK3C2BJAK1JAK2MC4R | |
| Hydrochloric Acid SCHEMBL6956268 | 0.99 | PIK3CD (0.36) | PIK3CDPIK3C2BJAK1JAK2MC4R | |
| Hydrochloric Acid SCHEMBL6956267 | 0.99 | PIK3CD (0.36) | PIK3CDPIK3C2BJAK1JAK2MC4R | |
| SCHEMBL6954486 | 0.89 | PIK3CD (0.33) | PIK3CDPIK3C2BJAK1JAK2KCNH3 | |
| SCHEMBL6954489 | 0.89 | PIK3CD (0.33) | PIK3CDPIK3C2BJAK1JAK2KCNH3 | |
| SCHEMBL6967941 | 0.89 | TRPC3 (0.34) | JAK1JAK2KCNH3THRBMARK3 | |
| Hydrochloric Acid SCHEMBL6961952 | 0.88 | KCNH3 (0.34) | PIK3CDPIK3C2BJAK1JAK2KCNH3 | |
| Hydrochloric Acid SCHEMBL6961955 | 0.88 | KCNH3 (0.34) | PIK3CDPIK3C2BJAK1JAK2KCNH3 | |
| SCHEMBL6961824 | 0.86 | PABPC1 (0.42) | — | |
| SCHEMBL6957770 | 0.86 | THRB (0.35) | JAK1JAK2KCNH3DHFRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | claimed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | claimed |