Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954016 | 0.96 | DRD2 (0.45) | ABCB1ABCC1DRD2HTR2AADRA1A | |
| SCHEMBL6736538 | 0.96 | ABCB1 (0.44) | ABCB1ABCC1DRD2HTR2AADRA1A | |
| Hydrochloric Acid SCHEMBL6944579 | 0.95 | ABCB1 (0.44) | ABCB1ABCC1DRD2HTR2AADRA1A | |
| Hydrochloric Acid SCHEMBL6740408 | 0.94 | ABCB1 (0.43) | ABCB1ABCC1DRD2HTR2AADRA1A | |
| SCHEMBL6735246 | 0.92 | DRD2 (0.47) | ABCB1ABCC1DRD2HTR2AADRA1A | |
| SCHEMBL6955839 | 0.92 | HTR2A (0.47) | PDE3BPDE3AABCB1ABCC1DRD2 | |
| Hydrochloric Acid SCHEMBL6948459 | 0.91 | DRD2 (0.47) | ABCB1ABCC1DRD2HTR2AADRA1A | |
| Hydrochloric Acid SCHEMBL6738843 | 0.91 | DRD2 (0.46) | DRD2HTR2AADRA1AKCNH2DRD3 | |
| SCHEMBL6955657 | 0.88 | HTR7 (0.47) | DRD2HTR2AADRA1ADRD3 | |
| SCHEMBL6734946 | 0.87 | HTR7 (0.47) | ABCB1ABCC1DRD2HTR2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311503-A1 | CHROMENONE DERIVATIVES AND THEIR USE FOR TREATING DISEASES IN CONJUNCTION WITH 5-HTA1 RECEPTORS AND/OR DOPAMINE D2 RECEPTORS | MERCK PATENT GmbH (DE) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002016354-A1 | CHROMENONE DERIVATIVES AND THEIR USE FOR TREATING DISEASES IN CONJUNCTION WITH 5-HTA1 RECEPTORS AND/OR DOPAMINE D2 RECEPTORS | MERCK PATENT GMBH (DE) | 2002-02-28 | — | — | WO | disclosed |