Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6195748 | 0.86 | F2RL1 (0.48) | F2RL1 | |
| SCHEMBL6954666 | 0.79 | F2RL1 (0.43) | F2RL1 | |
| SCHEMBL3529779 | 0.75 | F2RL1 (0.45) | F2RL1 | |
| SCHEMBL6194278 | 0.74 | NPC1 (0.40) | F2RL1 | |
| SCHEMBL954700 | 0.74 | F2RL1 (0.51) | F2RL1 | |
| SCHEMBL6956313 | 0.74 | F2RL1 (0.50) | F2RL1 | |
| SCHEMBL3529538 | 0.73 | F2RL1 (0.44) | F2RL1 | |
| SCHEMBL6239945 | 0.72 | F2RL1 (0.41) | F2RL1 | |
| SCHEMBL3527344 | 0.70 | F2RL1 (0.39) | F2RL1 | |
| SCHEMBL6192150 | 0.70 | FPR2 (0.41) | F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276725-A2 | 5-SUBSTITUTED TETRALONES AS INHIBITORS OF RAS FARNESYL TRANSFERASE | WARNER-LAMBERT COMPANY (US) | 2003-01-22 | — | — | EP | disclosed |
| WO-2001079180-A2 | 5-SUBSTITUTED TETRALONES AS INHIBITORS OF RAS FARNESYL TRANSFERASE | WARNER-LAMBERT COMPANY (US) | 2001-10-25 | — | — | WO | disclosed |