Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ASPH | Q12797 | 1/20 | 0.36 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.36 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954518 | 0.85 | ABCB1 (0.44) | GAAALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL16857041 | 0.78 | ALDH1A1 (0.53) | GAAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6953338 | 0.75 | KDM4E (0.42) | HDAC1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL6519025 | 0.73 | KDM4E (0.50) | GAAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7627705 | 0.73 | MAPT (0.44) | GAADRD2KDM4EALDH1A1MAPT | |
| SCHEMBL12099986 | 0.73 | KDM4E (0.48) | GAAHDAC1KDM4EALDH1A1MAPT | |
| SCHEMBL8128802 | 0.73 | KDM4E (0.44) | GAADRD2KDM4EALDH1A1MAPT | |
| SCHEMBL2320471 | 0.71 | DRD2 (0.46) | GAADRD2KDM4EALDH1A1MAPT | |
| SCHEMBL20046200 | 0.70 | CA1 (0.43) | GAAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL5226494 | 0.69 | HDAC1 (0.57) | GAAHDAC1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019047-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2003-11-05 | — | — | EP | disclosed |
| US-6541499-B1 | Antithrombotic agents | ELI LILLY AND COMPANY | 2003-04-01 | — | — | US | disclosed |
| EP-1019047-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-1019047-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998048800-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |