Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957278 | 0.85 | ADRA2A (0.46) | ADRA2A | |
| SCHEMBL6951348 | 0.82 | SCN4A (0.31) | ADRA2A | |
| SCHEMBL6960771 | 0.75 | HTR2A (0.42) | ADRA2A | |
| SCHEMBL6954590 | 0.75 | HTR2A (0.42) | ADRA2A | |
| SCHEMBL6955865 | 0.70 | AKR1B1 (0.51) | ADRA2A | |
| SCHEMBL2511832 | 0.68 | TAAR1 (0.50) | ADRA2A | |
| SCHEMBL5953900 | 0.66 | ADRA2A (0.40) | ADRA2A | |
| SCHEMBL6954716 | 0.65 | ADRA2A (0.46) | ADRA2A | |
| SCHEMBL6952820 | 0.65 | ADRA2A (0.30) | ADRA2A | |
| SCHEMBL6955673 | 0.65 | MCHR1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1010693-B1 | Imidazoline derivatives, preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-09-24 | — | — | EP | disclosed |
| US-6127396-A | Imidazoline compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |