Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | TTR | P02766 | 2/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.37 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954943 | 0.84 | ADRA2A (0.48) | AKR1B1ADRA2ACXCL8ABCB11PTGS1 | |
| SCHEMBL8097604 | 0.80 | ADRA2A (0.43) | ADRA2ACA2ALDH1A1HPGDNOTUM | |
| SCHEMBL6957840 | 0.78 | RXRB (0.41) | KMT2ACA2RXRARXRBRXRG | |
| SCHEMBL27499925 | 0.74 | ADRA2A (0.50) | ADRA2AADRA1ANOTUMHTR1ACYP2D6 | |
| SCHEMBL7294400 | 0.73 | HTR1A (0.44) | AKR1B1ADRA2APTGS1GAALMNA | |
| SCHEMBL6955284 | 0.70 | ADRA2A (0.46) | ADRA2A | |
| SCHEMBL109215 | 0.69 | AKR1B1 (1.00) | AKR1B1ADRA2ACXCL8ADRA1ATTR | |
| SCHEMBL9364446 | 0.68 | AKR1B1 (0.95) | AKR1B1ADRA2ACXCL8ADRA1ATTR | |
| Hydrochloric Acid SCHEMBL1374156 | 0.68 | AKR1B1 (0.95) | AKR1B1ADRA2ACXCL8ADRA1ATTR | |
| SCHEMBL19732314 | 0.67 | TSHR (0.40) | AKR1B1KMT2AALDH1A1NOTUMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1010693-B1 | Imidazoline derivatives, preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-09-24 | — | — | EP | disclosed |
| EP-1010693-A1 | Imidazoline derivatives, preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |