Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTC4S | Q16873 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232344 | 0.86 | ALDH1A1 (0.57) | RAB9AALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6963003 | 0.86 | ALDH1A1 (0.54) | LTC4SRAB9AALDH1A1KMT2ALMNA | |
| SCHEMBL6953534 | 0.86 | RAB9A (0.50) | LTC4SRAB9AALDH1A1KMT2ALMNA | |
| SCHEMBL6963618 | 0.81 | CYP1A2 (0.50) | LTC4SRAB9AALDH1A1KMT2ALMNA | |
| SCHEMBL7845144 | 0.78 | SMN1; SMN2 (0.50) | RAB9AALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6284560 | 0.74 | NPC1 (0.56) | RAB9AALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL29117982 | 0.71 | ALDH1A1 (0.51) | RAB9AALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL30648074 | 0.71 | ALDH1A1 (0.51) | RAB9AALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11485382 | 0.71 | RAB9A (0.59) | LTC4SRAB9AALDH1A1KMT2ALMNA | |
| SCHEMBL6392481 | 0.70 | PARP1 (0.49) | ALDH1A1KMT2ASMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | disclosed |