Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL385027 | 0.80 | FFAR4 (0.62) | ALDH1A1L3MBTL1MAPTMAOBSMN1; SMN2 | |
| SCHEMBL2087592 | 0.80 | MAOB (0.68) | ALDH1A1LMNAKMT2AMEN1POLB | |
| SCHEMBL29783148 | 0.80 | FFAR4 (0.62) | ALDH1A1L3MBTL1MAPTMAOBSMN1; SMN2 | |
| SCHEMBL31003218 | 0.79 | ALDH1A1 (0.56) | ALDH1A1LMNAKMT2AMEN1POLB | |
| SCHEMBL195793 | 0.79 | ALDH1A1 (0.56) | ALDH1A1LMNAKMT2AMEN1POLB | |
| SCHEMBL6958801 | 0.78 | SYK (0.71) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL6963902 | 0.78 | SYK (0.52) | ALDH1A1LMNAKMT2AMEN1GAA | |
| SCHEMBL13144446 | 0.77 | ABCB1 (0.60) | MAPTRECQL | |
| SCHEMBL6099631 | 0.77 | KMT2A (0.59) | ALDH1A1LMNAKMT2AMEN1POLB | |
| SCHEMBL7595205 | 0.77 | HIF1A (0.60) | ALDH1A1LMNAKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729465-B1 | PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE DAVIS & CO (US) | 2003-01-22 | — | — | EP | disclosed |
| US-6005103-A | TREATMENT OF BACTERIAL AND VIRAL INFECTIONS AND DISEASES, INCLUDING AIDS | WARNER-LAMBERT COMPANY (US) | 1999-12-21 | — | — | US | disclosed |
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |
| EP-0729466-A1 | PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995014014-A2 | PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1995-05-26 | — | — | WO | disclosed |