Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 10/20 | 1.00 |
| ▸ | MEN1 | O00255 | 9/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 1.00 |
| ▸ | LMNA | P02545 | 7/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.83 |
| ▸ | HTT | P42858 | 4/20 | 0.83 |
| ▸ | RAB9A | P51151 | 4/20 | 0.79 |
| ▸ | NPC1 | O15118 | 3/20 | 0.79 |
| ▸ | MAOA | P21397 | 2/20 | 0.79 |
| ▸ | MAOB | P27338 | 2/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.75 |
| ▸ | GAA | P10253 | 1/20 | 0.75 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.72 |
| ▸ | CNR1 | P21554 | 1/20 | 0.68 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.65 |
| ▸ | XBP1 | P17861 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520437 | 0.89 | RAB9A (1.00) | MAPTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL6516283 | 0.87 | KMT2A (0.88) | MAPTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL9530086 | 0.86 | MAPT (0.76) | MAPTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL8615629 | 0.86 | RAB9A (0.81) | MAPTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL7573221 | 0.85 | MAPT (0.74) | MAPTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL6815628 | 0.84 | RAB9A (0.79) | MAPTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL28257929 | 0.84 | RAB9A (0.79) | MAPTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL14560608 | 0.84 | MAPT (1.00) | MAPTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL6965791 | 0.84 | LMNA (0.74) | MAPTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL14612489 | 0.83 | RAB9A (0.77) | MAPTKMT2AMEN1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |
| US-5658907-A | THIOUREA VIRICIDES | MEDIVIR A/B (SE) | 1997-08-19 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | disclosed |