Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | PKM | P14618 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309018 | 0.83 | MAPT (0.43) | HTTMAPTPOLBCYP3A4CYP2C9 | |
| SCHEMBL6954775 | 0.76 | ADORA2A (0.33) | HTTMAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8430909 | 0.75 | TSHR (0.49) | HTTMAPTPOLBCYP3A4CYP2C9 | |
| SCHEMBL6959749 | 0.71 | HTT (0.45) | HTTMAPTPOLBCYP2C19KDM4E | |
| SCHEMBL7171446 | 0.70 | HTT (0.48) | HTTMAPTPOLBCYP3A4CYP2C9 | |
| SCHEMBL9519740 | 0.65 | PTGS2 (0.39) | HTTPOLBKDM4ENPSR1SMN1; SMN2 | |
| Cyazofamid SCHEMBL16180421 | 0.64 | PTGS2 (0.38) | HTTCYP2C9CYP2C19KDM4ESMN1; SMN2 | |
| SCHEMBL6966414 | 0.64 | MEN1 (0.39) | HTTMAPTNPSR1SMN1; SMN2LMNA | |
| SCHEMBL5718754 | 0.64 | SMN1; SMN2 (0.38) | HTTPOLBKDM4ESMN1; SMN2LMNA | |
| SCHEMBL24254265 | 0.64 | POLB (0.54) | HTTMAPTPOLBCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906311-B1 | N-SULFONYLIMIDAZOLES USED AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2003-04-23 | — | — | EP | disclosed |
| US-6043377-A | MICROBICIDES USEFUL IN CROP PROTECTION AND IN THE PROTECTION OF MATERIALS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-28 | — | — | US | disclosed |