Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430909 | 0.87 | TSHR (0.49) | SMN1; SMN2ALDH1A1HPGDKMT2AMEN1 | |
| Cyazofamid SCHEMBL16180421 | 0.85 | PTGS2 (0.38) | SMN1; SMN2KMT2AMEN1TSHRCYP11B1 | |
| Cyazofamid SCHEMBL23804496 | 0.83 | PTGS2 (0.37) | SMN1; SMN2KMT2AMEN1TSHRCYP11B1 | |
| SCHEMBL9519740 | 0.82 | PTGS2 (0.39) | SMN1; SMN2ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL1073894 | 0.80 | PTGS2 (0.46) | SMN1; SMN2TSHRKDM4ELMNAHTT | |
| SCHEMBL1074601 | 0.78 | TSHR (0.34) | SMN1; SMN2HPGDKMT2ATSHRTP53 | |
| SCHEMBL1074589 | 0.78 | PTGS1 (0.41) | SMN1; SMN2ALDH1A1HPGDKMT2AMEN1 | |
| Cyazofamid SCHEMBL16910348 | 0.76 | PTGS2 (0.32) | SMN1; SMN2TSHR | |
| SCHEMBL7095742 | 0.74 | PTGS2 (0.37) | ALDH1A1KMT2AMEN1CYP11B1CYP11B2 | |
| SCHEMBL9519745 | 0.72 | SMN1; SMN2 (0.33) | SMN1; SMN2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732385-A1 | USE OF (3-(1-(3-PHENYL-PROPENYL)-PIPERIDIN-4-YL)-2,3-DIHYDRO-INDOL-1-YL)-(PYRIDIN-4-YL)-METHANONE DERIVATIVES AND RELATED COMPOUNDS AS INSECTICIDES | Syngenta Participations AG (CH) | 2006-12-20 | — | — | EP | disclosed |
| EP-1697376-A1 | SPIRO-CONDENSED INDOLINE DERIVATIVES AS PESTICIDES | Syngenta Participations AG (CH) | 2006-09-06 | — | — | EP | disclosed |
| EP-1694677-A1 | SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS | Syngenta Participations AG (CH) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005061512-A1 | SPIRO-CONDENSED INDOLINE DERIVATES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-07-07 | — | — | WO | disclosed |
| WO-2005061500-A1 | SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2005-07-07 | — | — | WO | disclosed |
| WO-2005058035-A1 | USE OF (3-(1-(3-PHENYL-PROPENYL)-PIPERIDIN-4-YL)-2,3-DIHYDRO-INDOL-1-YL)-(PYRIDIN-4-YL)-METHANONE DERIVATIVES AND RELATED COMPOUNDS AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-06-30 | — | — | WO | disclosed |
| WO-2001055142-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |