Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | TEC | P42680 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959393 | 0.80 | MAOB (0.57) | MAOBPDE10APDGFRBPDGFRAMEN1 | |
| SCHEMBL7729942 | 0.78 | RAB9A (0.44) | MAOBNOS3NOS1MEN1LMNA | |
| SCHEMBL6966030 | 0.76 | CYP3A4 (0.62) | MAOBPDGFRBPDGFRACYP3A4MEN1 | |
| SCHEMBL8824927 | 0.75 | MAOB (0.39) | MAOBPDE10ACYP3A4PDE4D | |
| SCHEMBL6954964 | 0.75 | MAOB (0.48) | MAOBPDE10ACYSLTR1CYP3A4PDE4D | |
| SCHEMBL8825036 | 0.74 | MAOB (0.38) | MAOBPDE10ACYP3A4PDE4D | |
| SCHEMBL8824926 | 0.74 | MAOB (0.39) | MAOBPDE10APDE4D | |
| SCHEMBL6954874 | 0.74 | PPARG (0.63) | CYP3A4 | |
| SCHEMBL20386648 | 0.73 | MAOB (0.69) | MAOBCYP3A4LMNA | |
| SCHEMBL6956226 | 0.72 | PPARG (0.52) | MAOBPDE10ACYP3A4PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787725-B1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-5693651-A | HYPOGLYCEMIC AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0787725-A1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |