Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GPR139 | Q6DWJ6 | 7/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948981 | 0.91 | ALDH1A1 (0.50) | KMT2AKDM4ENPSR1ALDH1A1LMNA | |
| SCHEMBL6956586 | 0.88 | ALDH1A1 (0.50) | KMT2AKDM4ENPSR1ALDH1A1LMNA | |
| SCHEMBL6945048 | 0.82 | NPC1 (0.46) | KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6953863 | 0.82 | KMT2A (0.49) | KMT2AKDM4ENPSR1ALDH1A1LMNA | |
| SCHEMBL6952660 | 0.80 | NPC1 (0.45) | KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6947290 | 0.75 | NPC1 (0.67) | SMN1; SMN2 | |
| SCHEMBL6949260 | 0.74 | NPC1 (0.43) | KMT2AKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL4872025 | 0.73 | KMT2A (0.56) | KMT2AKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6953738 | 0.73 | NPC1 (0.42) | KMT2AKDM4EALDH1A1GPR139HSD17B10 | |
| SCHEMBL18787411 | 0.71 | KMT2A (0.67) | KMT2AKDM4ENPSR1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |