Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | QPCT | Q16769 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955189 | 0.90 | KDM4E (0.63) | ALDH1A1MAPK1HSD17B10KDM4EMAPT | |
| SCHEMBL6964189 | 0.87 | MEN1 (0.50) | ALDH1A1MAPK1HSD17B10KDM4EMAPT | |
| SCHEMBL6957937 | 0.87 | RAB9A (0.66) | ALDH1A1KDM4EMAPTGAARAB9A | |
| SCHEMBL6963001 | 0.87 | NPC1 (0.57) | ALDH1A1MAPK1HSD17B10KDM4EMAPT | |
| SCHEMBL6952296 | 0.87 | NPC1 (0.57) | ALDH1A1MAPK1HSD17B10KDM4EMAPT | |
| SCHEMBL6957955 | 0.87 | KDM4E (0.53) | ALDH1A1MAPK1HSD17B10KDM4EMAPT | |
| SCHEMBL6950923 | 0.87 | MAPT (0.50) | ALDH1A1MAPK1HSD17B10KDM4EMAPT | |
| SCHEMBL6953252 | 0.86 | ALDH1A1 (0.49) | ALDH1A1MAPK1HSD17B10KDM4EMAPT | |
| SCHEMBL6961507 | 0.84 | KMT2A (0.67) | ALDH1A1MAPK1HSD17B10KDM4EMAPT | |
| SCHEMBL11702364 | 0.84 | ALDH1A1 (0.64) | ALDH1A1MAPK1HSD17B10KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |
| US-5658907-A | THIOUREA VIRICIDES | MEDIVIR A/B (SE) | 1997-08-19 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |