Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 9/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19497421 | 0.88 | GPR35 (0.78) | GPR35ALDH1A1CRHBPCRHR2CA12 | |
| SCHEMBL690829 | 0.88 | GPR35 (0.78) | GPR35ALDH1A1CRHBPCRHR2CA12 | |
| SCHEMBL7123712 | 0.87 | GPR35 (0.77) | GPR35ALDH1A1CA12CA1CA2 | |
| SCHEMBL7028676 | 0.86 | GPR35 (0.74) | GPR35ALDH1A1CRHBPCRHR2MEN1 | |
| SCHEMBL7021569 | 0.84 | GPR35 (0.72) | GPR35ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL7024419 | 0.84 | GPR35 (0.72) | GPR35ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL7031408 | 0.82 | GPR35 (0.68) | GPR35ALDH1A1CRHBPCRHR2MEN1 | |
| SCHEMBL28570533 | 0.81 | GPR35 (0.68) | GPR35ALDH1A1CRHBPCRHR2CA12 | |
| SCHEMBL15851029 | 0.81 | GPR35 (0.68) | GPR35ALDH1A1CRHBPCRHR2CA12 | |
| SCHEMBL7028726 | 0.81 | GPR35 (0.66) | GPR35ALDH1A1TDP1TTRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4376678-A | Method of inhibiting polymerization of vinyl aromatic compounds | AMERICAN HOECHST CORPORATION (US) | 1983-03-15 | — | — | US | claimed |
| EP-2479203-A1 | AROMATIC POLYESTER | Muroran Institute of Technology (JP) | 2012-07-25 | — | — | EP | disclosed |
| US-20120172570-A1 | AROMATIC POLYESTER | NITTA CORPORATION | 2012-07-05 | — | — | US | disclosed |
| US-8129493-B2 | Aromatic polyester | MURORAN INSTITUTE OF TECHNOLOGY (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20110224343-A1 | MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME | MURORAN INSTITUTE OF TECHNOLOGY (JP) | 2011-09-15 | — | — | US | disclosed |
| US-20110092662-A1 | AROMATIC POLYESTER | NITTA CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
| US-4623430-A | PRETREATED ASPHALTS OR ASPHALTENES | COSDEN TECHNOLOGY, INC. (US) | 1986-11-18 | — | — | US | disclosed |
| US-4623431-A | ASPHALTENE AND OXYGEN | COSDEN TECHNOLOGY, INC. (US) | 1986-11-18 | — | — | US | disclosed |
| US-4376678-A | Method of inhibiting polymerization of vinyl aromatic compounds | AMERICAN HOECHST CORPORATION (US) | 1983-03-15 | — | — | US | disclosed |
| US-4376678-A | Method of inhibiting polymerization of vinyl aromatic compounds | AMERICAN HOECHST CORPORATION (US) | 1983-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224343-A1 | MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME | F12, PHAX, WDR82 | GPR35 2050/4885ALDH1A1 1882/4885CRHBP 2951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.