SCHEMBL28570533

SCHEMBL28570533

CCC(C)(C)c1cc([N+](=O)[O-])c(O)c([N+](=O)[O-])c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 8/20 0.68
ALDH1A1 P00352 2/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
ESR1 P03372 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
MAPK1 P28482 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
KDM4E B2RXH2 1/20 0.42
TTR P02766 1/20 0.42
CYP1A2 P05177 1/20 0.42
MAPT P10636 1/20 0.42
CYP2C9 P11712 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7908796 0.89 GPR35 (0.54) GPR35ALDH1A1CA12CA1CA2
SCHEMBL24711215 0.81 MAPK1 (0.50) GPR35ALDH1A1CA12CA1CA2
SCHEMBL19497421 0.81 GPR35 (0.78) GPR35ALDH1A1CRHBPCRHR2CA12
SCHEMBL69563 0.81 GPR35 (1.00) GPR35ALDH1A1CRHBPCRHR2CA12
SCHEMBL690829 0.81 GPR35 (0.78) GPR35ALDH1A1CRHBPCRHR2CA12
SCHEMBL28002150 0.79 GPR35 (0.43) GPR35ALDH1A1CRHBPCRHR2MEN1
SCHEMBL28573264 0.77 GPR35 (0.47) GPR35ALDH1A1CRHBPCRHR2CA12
SCHEMBL7028676 0.76 GPR35 (0.74) GPR35ALDH1A1CRHBPCRHR2ESR1
SCHEMBL15851029 0.75 GPR35 (0.68) GPR35ALDH1A1CRHBPCRHR2CA12
SCHEMBL15157099 0.75 TSHR (0.53) GPR35ALDH1A1MEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112661649-B 2,6-dinitro-4-tert-amylphenol and preparation method thereof 宁波龙欣精细化工有限公司 2023-01-10 CN claimed
CN-112661649-A 2, 6-dinitro-4-tert-amylphenol and preparation method thereof 宁波龙欣精细化工有限公司 2021-04-16 CN claimed
CN-112661649-B 2,6-dinitro-4-tert-amylphenol and preparation method thereof 宁波龙欣精细化工有限公司 2023-01-10 CN disclosed
CN-112661649-B 2,6-dinitro-4-tert-amylphenol and preparation method thereof 宁波龙欣精细化工有限公司 2023-01-10 CN disclosed
CN-112661649-B 2,6-dinitro-4-tert-amylphenol and preparation method thereof 宁波龙欣精细化工有限公司 2023-01-10 CN disclosed
CN-112661649-A 2, 6-dinitro-4-tert-amylphenol and preparation method thereof 宁波龙欣精细化工有限公司 2021-04-16 CN disclosed
CN-112661649-A 2, 6-dinitro-4-tert-amylphenol and preparation method thereof 宁波龙欣精细化工有限公司 2021-04-16 CN disclosed
CN-112661649-A 2, 6-dinitro-4-tert-amylphenol and preparation method thereof 宁波龙欣精细化工有限公司 2021-04-16 CN disclosed