Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.37 |
| ▸ | PPARG | P37231 | 10/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956396 | 0.83 | CHRM5 (0.35) | PPARAPPARGCHRM5F10DRD3 | |
| SCHEMBL6952324 | 0.77 | PPARG (0.46) | PPARAPPARG | |
| SCHEMBL6949460 | 0.75 | PPARA (0.42) | PPARAPPARGF10DRD2TDP1 | |
| SCHEMBL6945497 | 0.73 | PPARG (0.36) | PPARAPPARGDRD3POLB | |
| SCHEMBL6952379 | 0.73 | PPARG (0.32) | PPARAPPARG | |
| SCHEMBL6955247 | 0.71 | MAPT (0.44) | PPARAPPARGPOLBTDP1 | |
| SCHEMBL6947127 | 0.71 | ALDH1A1 (0.40) | PPARAPPARGPOLBTDP1 | |
| SCHEMBL6957295 | 0.68 | PPARG (0.41) | PPARAPPARGPOLBTDP1 | |
| SCHEMBL6948887 | 0.66 | PPARG (0.41) | PPARAPPARGDRD3DRD2 | |
| SCHEMBL6954580 | 0.66 | TNF (0.41) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |