Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 7/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956393 | 0.83 | PPARA (0.37) | CHRM5PPARAPPARGF10DRD3 | |
| SCHEMBL6952324 | 0.74 | PPARG (0.46) | PPARAPPARG | |
| SCHEMBL6949460 | 0.72 | PPARA (0.42) | PPARAPPARGF10DRD2PARK7 | |
| SCHEMBL6947132 | 0.68 | ALDH1A1 (0.41) | PPARAPPARG | |
| SCHEMBL6945497 | 0.68 | PPARG (0.36) | PPARAPPARGDRD3 | |
| SCHEMBL6952379 | 0.68 | PPARG (0.32) | PPARAPPARG | |
| SCHEMBL6955247 | 0.67 | MAPT (0.44) | PPARAPPARG | |
| SCHEMBL6954585 | 0.64 | TNF (0.41) | PPARARAB9APPARGNPC1 | |
| SCHEMBL6957510 | 0.64 | MAPK1 (0.57) | RAB9ANPC1 | |
| SCHEMBL6952396 | 0.64 | MEN1 (0.46) | PPARARAB9APPARGNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |