SCHEMBL6956394

SCHEMBL6956394

CC1CNCCCN1Cc1ccccn1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.51
HSD11B1 P28845 1/20 0.43
LMNA P02545 1/20 0.42
CXCR4 P61073 4/20 0.42
CASP6 P55212 1/20 0.41
DDB1 Q16531 1/20 0.40
CRBN Q96SW2 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
KMT2A Q03164 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
TAAR1 Q96RJ0 1/20 0.39
SLC6A4 P31645 1/20 0.39
ALDH1A1 P00352 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
HTR2B P41595 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9933760 0.92 HRH3 (0.47) HRH3HSD11B1LMNACXCR4CASP6
SCHEMBL9932689 0.92 HRH3 (0.47) HRH3HSD11B1LMNACXCR4CASP6
Hydrochloric Acid SCHEMBL29232435 0.90 LMNA (0.46) HRH3HSD11B1LMNACXCR4CASP6
SCHEMBL1088353 0.77 CASP6 (0.52) HRH3LMNACASP6DDB1CRBN
SCHEMBL31462966 0.74 PIM3 (0.37) HRH3LMNACXCR4CYP2C19KMT2A
SCHEMBL31155302 0.74 PIM3 (0.37) HRH3LMNACXCR4CYP2C19KMT2A
SCHEMBL27923587 0.74 SLC6A4 (0.42) HSD11B1CASP6DDB1CRBNCYP1A2
SCHEMBL9965922 0.73 HRH3 (0.51) HRH3LMNACXCR4DDB1CRBN
SCHEMBL21820616 0.73 HRH3 (0.57) HRH3HSD11B1LMNADDB1CRBN
SCHEMBL30734421 0.73 HRH3 (0.57) HRH3HSD11B1LMNADDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1280794-A1 DIAZACYCLOALKANE DERIVATIVES AS BLEACH CATALYST AND COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE UNILEVER PLC (GB) 2003-02-05 EP disclosed
WO-2001085717-A1 DIAZACYCLOALKANE DERIVATIVES AS BLEACH CATALYST AND COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE UNILEVER PLC (GB) 2001-11-15 WO disclosed