Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 10/20 | 0.41 |
| ▸ | ELANE | P08246 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956835 | 0.87 | HTR4 (0.43) | HTR4ELANEKDM4EKMT2AF2 | |
| SCHEMBL6956828 | 0.87 | HTR4 (0.43) | HTR4ELANEKDM4EKMT2AF2 | |
| SCHEMBL6950067 | 0.87 | HTR4 (0.43) | HTR4ELANEKDM4EKMT2AF2 | |
| SCHEMBL6951757 | 0.87 | KMT2A (0.43) | HTR4ELANEKDM4EKMT2AF2 | |
| SCHEMBL8876561 | 0.85 | ELANE (0.51) | HTR4ELANEKDM4EKMT2AF2 | |
| SCHEMBL1405874 | 0.83 | HTR4 (0.55) | HTR4KDM4EKMT2A | |
| SCHEMBL6948875 | 0.82 | HTR4 (0.44) | HTR4ELANEKDM4EKMT2AF2 | |
| SCHEMBL6956165 | 0.77 | HTR4 (0.42) | HTR4ELANEKDM4EKMT2AF2 | |
| SCHEMBL6950019 | 0.77 | CYP1A2 (0.45) | ELANEKDM4EF2PLAU | |
| SCHEMBL8714243 | 0.76 | KDM4E (0.43) | HTR4ELANEKDM4EKMT2AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0829474-B1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN SEIFUN GROUP INC (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-6096746-A | Indazole compound containing a monocyclic amine structure | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5945434-A | TREATMENT OF GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0708105-B1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO (JP) | 1998-12-23 | — | — | EP | disclosed |
| EP-0829474-A1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-03-18 | — | — | EP | disclosed |
| US-5684003-A | GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0708105-A1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |