Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 16/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714860 | 0.88 | KMT2A (0.44) | KDM4EHTR4KMT2AF2PLAU | |
| SCHEMBL8878734 | 0.86 | ELANE (0.48) | KDM4EHTR4KMT2AF2PLAU | |
| SCHEMBL1405874 | 0.83 | HTR4 (0.55) | KDM4EHTR4KMT2AKCNH2 | |
| SCHEMBL6956835 | 0.78 | HTR4 (0.43) | KDM4EHTR4KMT2AF2PLAU | |
| SCHEMBL6950067 | 0.78 | HTR4 (0.43) | KDM4EHTR4KMT2AF2PLAU | |
| SCHEMBL6956828 | 0.78 | HTR4 (0.43) | KDM4EHTR4KMT2AF2PLAU | |
| SCHEMBL6956165 | 0.77 | HTR4 (0.42) | KDM4EHTR4KMT2AF2PLAU | |
| SCHEMBL6956782 | 0.76 | HTR4 (0.41) | KDM4EHTR4KMT2AF2PLAU | |
| SCHEMBL6948875 | 0.76 | HTR4 (0.44) | KDM4EHTR4KMT2AF2PLAU | |
| SCHEMBL8720506 | 0.74 | KDM4E (0.38) | KDM4EF2PLAUELANEHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708105-B1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5684003-A | GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0708105-A1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |