Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.34 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6140510 | 0.78 | NISCH (0.37) | KMT2AMEN1SMN1; SMN2NISCHSMPD3 | |
| SCHEMBL4084793 | 0.73 | IDO1 (0.44) | POLBHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL24575956 | 0.72 | CCR1 (0.42) | KMT2AMEN1SMN1; SMN2NISCHSMPD3 | |
| SCHEMBL7505372 | 0.72 | KMT2A (0.40) | POLBHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL62021 | 0.71 | POLB (0.53) | POLBHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5372667 | 0.69 | CDC7 (0.43) | KMT2AMEN1SMN1; SMN2NISCHSMPD3 | |
| SCHEMBL5192498 | 0.69 | NISCH (0.41) | KMT2AMEN1SMN1; SMN2NISCHSMPD3 | |
| SCHEMBL6473915 | 0.67 | NR4A2 (0.46) | POLBHTTKMT2AMEN1PDK1 | |
| SCHEMBL7521036 | 0.67 | KDM4E (0.56) | POLBHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6033417 | 0.66 | NR4A2 (0.45) | POLBHTTKMT2AMEN1PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030229092-A1 | Antidiabetic agents; antiinflammatory agents; analgesics; antiallergens | PHARMACOPEIA, INC. (US) | 2003-12-11 | — | — | US | disclosed |
| EP-1196411-A1 | BRADYKININ B1 RECEPTOR ANTAGONISTS | PHARMACOPEIA, INC. (US) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001005783-A1 | BRADYKININ B1 RECEPTOR ANTAGONISTS | PHARMACOPEIA, INC. (US) | 2001-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229092-A1 | Antidiabetic agents; antiinflammatory agents; analgesics; antiallergens | BDKRB1, BDKRB2, HRH2 | POLB 1746/4885HTT 3951/4885KMT2A 3838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.