Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 18/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.53 |
| ▸ | HTR2A | P28223 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946867 | 0.92 | HTR4 (0.52) | HTR4KCNH2HTR2A | |
| SCHEMBL6949375 | 0.91 | HTR4 (0.52) | HTR4KCNH2HTR2ASMN1; SMN2KDM4E | |
| SCHEMBL8173566 | 0.90 | HTR4 (0.61) | HTR4KCNH2HTR2AKDM4E | |
| SCHEMBL6951920 | 0.90 | HTR4 (0.55) | HTR4KCNH2HTR2ASMN1; SMN2KDM4E | |
| SCHEMBL6950149 | 0.83 | HTR4 (0.61) | HTR4KCNH2HTR2A | |
| SCHEMBL6944917 | 0.82 | HTR4 (0.51) | HTR4KCNH2HTR2ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7393717 | 0.82 | HTR4 (0.65) | HTR4KCNH2HTR2A | |
| SCHEMBL6955313 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2KDM4EALDH1A1HPGDHTT | |
| Hydrochloric Acid SCHEMBL7394154 | 0.81 | HTR4 (0.66) | HTR4KCNH2HTR2A | |
| SCHEMBL6952232 | 0.81 | HTR4 (0.59) | HTR4KCNH2HTR2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0829474-B1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN SEIFUN GROUP INC (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-6096746-A | Indazole compound containing a monocyclic amine structure | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5945434-A | TREATMENT OF GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0829474-A1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-03-18 | — | — | EP | disclosed |