Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 9/20 | 0.59 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8173566 | 0.91 | HTR4 (0.61) | HTR4HTR2AKDM4EATMNPSR1 | |
| SCHEMBL6949375 | 0.90 | HTR4 (0.52) | HTR4HTR2AKDM4EKCNH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7394644 | 0.89 | HTR4 (0.73) | HTR4HTR2AKCNH2 | |
| SCHEMBL6944917 | 0.88 | HTR4 (0.51) | HTR4HTR2AKCNH2 | |
| SCHEMBL6953798 | 0.86 | HTR4 (0.53) | HTR4HTR2AKDM4EKCNH2 | |
| SCHEMBL6946861 | 0.84 | KDM4E (0.54) | HTR4KDM4EATMNPSR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7394647 | 0.83 | KDM4E (0.53) | HTR4HTR2AKDM4EATMNPSR1 | |
| SCHEMBL6952236 | 0.82 | CNR1 (0.54) | HTR4KDM4EATMNPSR1ALDH1A1 | |
| SCHEMBL6957277 | 0.81 | HTR4 (0.53) | HTR4HTR2AKDM4EKCNH2ALDH1A1 | |
| SCHEMBL6946867 | 0.79 | HTR4 (0.52) | HTR4HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0829474-B1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN SEIFUN GROUP INC (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-6096746-A | Indazole compound containing a monocyclic amine structure | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5945434-A | TREATMENT OF GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0829474-A1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-03-18 | — | — | EP | disclosed |