Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1A | Q16819 | 1/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 2/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964182 | 0.82 | MEP1A (0.38) | MEP1AMEP1BPDK1IDH1CHRM2 | |
| SCHEMBL6964459 | 0.80 | IDH1 (0.37) | MEP1AMEP1BPDK1IDH1CHRM2 | |
| SCHEMBL6970219 | 0.73 | MEP1A (0.41) | MEP1AMEP1BPDK1IDH1CHRM2 | |
| SCHEMBL6965457 | 0.73 | MEP1A (0.37) | MEP1AMEP1BPDK1IDH1CHRM2 | |
| SCHEMBL6966662 | 0.73 | NPSR1 (0.44) | MEP1AMEP1BPDK1NR3C1HSD17B10 | |
| SCHEMBL6968946 | 0.71 | MEP1A (0.39) | MEP1AMEP1BPDK1IDH1CHRM2 | |
| SCHEMBL6970716 | 0.71 | F11 (0.39) | MEP1AMEP1BPDK1IDH1CHRM2 | |
| SCHEMBL6966010 | 0.71 | MEP1A (0.39) | MEP1AMEP1BPDK1IDH1CHRM2 | |
| SCHEMBL6972391 | 0.71 | MEP1A (0.39) | MEP1AMEP1BPDK1IDH1CHRM2 | |
| SCHEMBL6966005 | 0.71 | MEP1A (0.39) | MEP1AMEP1BPDK1IDH1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |