Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11840111 | 0.84 | HTR6 (0.77) | HTR6L3MBTL1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL2634765 | 0.82 | HTR6 (0.62) | HTR6L3MBTL1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL3363295 | 0.80 | CA2 (0.67) | HTR6CA2CA1CA9CA12 | |
| Hydrochloric Acid SCHEMBL3921297 | 0.80 | HTR6 (0.60) | HTR6L3MBTL1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL35949 | 0.80 | HTR6 (0.60) | HTR6L3MBTL1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL30335715 | 0.80 | CA2 (0.67) | HTR6CA2CA1CA9CA12 | |
| SCHEMBL29704174 | 0.80 | HTR6 (0.60) | HTR6L3MBTL1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL28072901 | 0.78 | HTR6 (0.58) | HTR6L3MBTL1MAPTTDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28173629 | 0.78 | HTR6 (0.58) | HTR6L3MBTL1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL14372093 | 0.77 | HTR6 (1.00) | HTR6L3MBTL1MAPTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |