Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.70 |
| ▸ | LTA4H | P09960 | 4/20 | 0.69 |
| ▸ | BACE1 | P56817 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12661473 | 0.82 | POLB (0.73) | LTA4HPOLBHTR2AHTR2CHTR2B | |
| SCHEMBL6962455 | 0.82 | LTA4H (0.62) | MCHR1LTA4HBACE1 | |
| SCHEMBL25590025 | 0.81 | LTA4H (0.56) | MCHR1LTA4HPOLBHTR2AHTR2C | |
| SCHEMBL14618663 | 0.81 | HTR2C (0.63) | MCHR1HTR2AHTR2CHTR2B | |
| SCHEMBL763134 | 0.80 | SMN1; SMN2 (0.71) | MCHR1LTA4HPOLB | |
| SCHEMBL6605680 | 0.80 | LTA4H (0.55) | MCHR1LTA4HHTR2CHTR2B | |
| SCHEMBL5385461 | 0.79 | MCHR1 (0.77) | MCHR1HTR2C | |
| SCHEMBL5387647 | 0.79 | MCHR1 (1.00) | MCHR1HTR2CHTR2B | |
| SCHEMBL2323789 | 0.79 | LTA4H (0.66) | MCHR1LTA4HPOLBHTR2AHTR2C | |
| SCHEMBL264641 | 0.79 | LTA4H (0.62) | MCHR1LTA4HPOLBHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980367-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-1244655-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001036414-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2001-05-25 | — | — | WO | disclosed |
| EP-0980367-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049161-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |