Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 15/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | HTR5A | P47898 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603679 | 0.86 | APP (0.45) | LTA4HMCHR1CYP2D6CYP2C19 | |
| SCHEMBL6594650 | 0.82 | LTA4H (0.60) | LTA4HDRD3HRH3 | |
| SCHEMBL6596911 | 0.81 | LTA4H (0.55) | LTA4HMCHR1SIGMAR1HRH3 | |
| SCHEMBL6957842 | 0.80 | MCHR1 (0.70) | LTA4HMCHR1HTR2CHTR2B | |
| SCHEMBL10436312 | 0.79 | TNFRSF1A (0.61) | — | |
| SCHEMBL7445580 | 0.76 | POLB (0.54) | LTA4HMCHR1KCNH2HRH3 | |
| SCHEMBL7768257 | 0.75 | ESR1 (0.56) | LTA4HKCNH2HRH3 | |
| SCHEMBL220877 | 0.75 | NOS3 (0.61) | LTA4HMCHR1ADORA2AADORA1HRH3 | |
| SCHEMBL6593929 | 0.74 | ESR1 (0.56) | LTA4HHRH3 | |
| SCHEMBL6595152 | 0.74 | LTA4H (0.55) | LTA4HHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244655-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2004-02-18 | — | — | EP | disclosed |
| US-6620837-B1 | 1-Benzothiophene derivatives | ELI LILLY AND COMPANY | 2003-09-16 | — | — | US | disclosed |
| EP-0980367-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2003-03-19 | — | — | EP | disclosed |
| US-6350774-B1 | Antithrombotic agents | ELI LILLY AND COMPANY | 2002-02-26 | — | — | US | disclosed |
| EP-0980367-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049161-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |