Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957884 | 0.86 | PTGER4 (0.33) | ALDH1A1GAAPTGER4MAPTSMN1; SMN2 | |
| SCHEMBL6969363 | 0.80 | ALOX5 (0.47) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL8272925 | 0.77 | NQO1 (0.34) | ALDH1A1PTGER4ALOX5 | |
| SCHEMBL2279816 | 0.75 | SLC6A4 (0.35) | PTGER4ALOX5 | |
| SCHEMBL23789077 | 0.75 | ACKR3 (0.38) | ALDH1A1HPGDPTGER4MAPTSMN1; SMN2 | |
| SCHEMBL27584938 | 0.75 | MCHR1 (0.46) | KDM4EALDH1A1HPGDPTGER4MAPT | |
| SCHEMBL27584946 | 0.75 | MCHR1 (0.39) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL19403995 | 0.74 | DDR1 (0.39) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL23789078 | 0.74 | ERCC1 (0.40) | MAPTLMNA | |
| SCHEMBL16373610 | 0.73 | SLC6A4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |