Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.45 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 10/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973262 | 0.92 | CACNA1F (0.53) | CYP3A4KCNH2POLBCACNA1FMAPK1 | |
| SCHEMBL5787321 | 0.85 | CYP3A4 (0.51) | CYP3A4KCNH2POLBCACNA1FMAPK1 | |
| SCHEMBL5787325 | 0.85 | CYP3A4 (0.51) | CYP3A4KCNH2POLBCACNA1FMAPK1 | |
| SCHEMBL6957895 | 0.85 | KCNH2 (0.42) | CYP3A4KCNH2POLBCACNA1FMAPK1 | |
| SCHEMBL6948985 | 0.84 | CYP3A4 (0.58) | CYP3A4KCNH2POLBKDM4EALDH1A1 | |
| SCHEMBL6975592 | 0.81 | CACNA1F (0.40) | CYP3A4KCNH2POLBCACNA1FMAPK1 | |
| SCHEMBL502617 | 0.81 | GSK3B (0.51) | CYP3A4KCNH2POLBCACNA1FMAPK1 | |
| SCHEMBL5783269 | 0.81 | GSK3B (0.51) | CYP3A4KCNH2POLBCACNA1FMAPK1 | |
| SCHEMBL4671496 | 0.81 | CACNA1F (0.57) | CYP3A4KCNH2POLBCACNA1FMAPK1 | |
| SCHEMBL6163513 | 0.80 | CYP3A4 (0.50) | CYP3A4KCNH2POLBCACNA1FMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304329-A2 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0807630-A1 | HETEROCYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |