Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973262 | 0.88 | CACNA1F (0.53) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL6957899 | 0.81 | CYP3A4 (0.51) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL8136400 | 0.81 | GSK3B (0.36) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9238479 | 0.81 | GSK3B (0.36) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL6963050 | 0.80 | CYP3A4 (0.48) | POLBKCNH2CYP3A4MEN1KMT2A | |
| SCHEMBL5787369 | 0.78 | CYP3A4 (0.37) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL6974626 | 0.77 | MEN1 (0.45) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL6983293 | 0.77 | CACNA1F (0.40) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL6983582 | 0.77 | CACNA1F (0.40) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL7997969 | 0.77 | CYP3A4 (0.34) | CACNA1FPOLBMAPK1CACNA1DKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807630-B1 | HETEROCYCLIC COMPOUNDS | DAIICHI SEIYAKU CO (JP) | 2003-05-07 | — | — | EP | claimed |