Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314084 | 0.95 | ADRA1A (0.34) | OPRD1POLBMAPTADRA2AADRA2B | |
| SCHEMBL1079263 | 0.92 | OPRD1 (0.38) | OPRD1MAPTADRA2AADRA2BADRA2C | |
| SCHEMBL4410856 | 0.89 | ADRA1A (0.37) | OPRD1MAPTADRA2AADRA2BADRA2C | |
| SCHEMBL4957978 | 0.89 | — | — | |
| SCHEMBL1489209 | 0.84 | — | — | |
| SCHEMBL88222 | 0.84 | — | — | |
| SCHEMBL327601 | 0.84 | OPRD1 (0.41) | OPRD1MAPTADRA2AADRA2BADRA2C | |
| SCHEMBL290880 | 0.84 | — | — | |
| SCHEMBL6692977 | 0.84 | OPRD1 (0.41) | OPRD1MAPTADRA2AADRA2BADRA2C | |
| SCHEMBL3970107 | 0.84 | OPRD1 (0.41) | OPRD1MAPTADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686421-B1 | ADDING A TERTIARY CHELATING AMINE OR A METAL SALT OF A CYCLIC ALCOHOL TO THE TIN-COUPLED RUBBERY POLYMER FOR IMPROVING THE STABILITY OF A TIN-COUPLED RUBBERY POLYMER | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-02-03 | — | — | US | disclosed |
| US-6180707-B1 | PREVENTING RECYCLE STREAM CONTAMINATION AND NOT CO-DISTILL WITH HEXANE BY MIXING IN A HIGH BOILING SODIUM MENTHOLATE | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-01-30 | — | — | US | disclosed |
| US-5981639-A | ADDING A SODIUM ALKOXIDE TO THE TIN-COUPLED RUBBERY POLYMER SUBSEQUENT TO THE TIME AT WHICH THE TIN-COUPLED RUBBERY POLYMER IS COUPLED | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-11-09 | — | — | US | disclosed |
| US-5739182-A | CHELATING TIN COUPLED RUBBERY POLYMER BY ADDING TERTIARY AMINE COMPOUND; STORAGE STABILITY | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-04-14 | — | — | US | disclosed |