Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.41 |
| ▸ | RBP4 | P02753 | 2/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952732 | 0.90 | ADRB1 (0.49) | ADRB1KMT2AGAAMTNR1BMAPT | |
| SCHEMBL6956738 | 0.89 | PHGDH (0.38) | KMT2AMAPTTP53ALDH1A1LMNA | |
| SCHEMBL6965376 | 0.86 | MAPT (0.44) | KMT2AGAAMAPTTP53ALDH1A1 | |
| SCHEMBL6960671 | 0.84 | KMT2A (0.47) | KMT2AGAAMAPTTP53ALDH1A1 | |
| SCHEMBL8704433 | 0.84 | MAPT (0.48) | ADRB1KMT2AGAAMAPTTP53 | |
| SCHEMBL8704078 | 0.83 | KMT2A (0.45) | KMT2AGAAMAPTTP53ALDH1A1 | |
| SCHEMBL8089025 | 0.81 | KMT2A (0.40) | ADRB1KMT2AGAAMTNR1BMAPT | |
| SCHEMBL8704961 | 0.80 | KMT2A (0.49) | KMT2AGAAMAPTTP53ALDH1A1 | |
| SCHEMBL8089048 | 0.78 | KMT2A (0.45) | KMT2AGAAMTNR1BMAPTTP53 | |
| SCHEMBL8703304 | 0.78 | MAPT (0.55) | KMT2AGAAMAPTTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |