Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956245 | 0.90 | NAMPT (0.42) | MAPTSMN1; SMN2LMNANAMPTTLR9 | |
| SCHEMBL6966613 | 0.90 | KMT2A (0.45) | MAPTSMN1; SMN2LMNANAMPTTLR9 | |
| SCHEMBL6958231 | 0.86 | ADRB1 (0.46) | MAPTLMNAKMT2AGAAP2RY12 | |
| SCHEMBL8699714 | 0.86 | MAPT (0.50) | MAPTLMNATLR9GAAP2RY12 | |
| SCHEMBL8699373 | 0.86 | MAPT (0.47) | MAPTNAMPTKMT2AGAAMEN1 | |
| SCHEMBL6960671 | 0.82 | KMT2A (0.47) | MAPTSMN1; SMN2LMNANAMPTKMT2A | |
| SCHEMBL8704078 | 0.81 | KMT2A (0.45) | MAPTLMNANAMPTKMT2AGAA | |
| SCHEMBL6964672 | 0.80 | KIT (0.44) | NAMPTTLR9P2RX7TLR7SLC2A1 | |
| SCHEMBL6956575 | 0.80 | MEN1 (0.45) | MAPTSMN1; SMN2LMNANAMPTTLR9 | |
| SCHEMBL8704961 | 0.78 | KMT2A (0.49) | MAPTSMN1; SMN2LMNANAMPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |