Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966867 | 0.88 | KMT2A (0.67) | KMT2AMEN1ALDH1A1LMNAATM | |
| SCHEMBL6956652 | 0.86 | KMT2A (0.61) | KMT2AMEN1ALDH1A1SMN1; SMN2ATM | |
| SCHEMBL6960069 | 0.86 | KMT2A (0.61) | KMT2AMEN1ALDH1A1LMNAATM | |
| SCHEMBL6954139 | 0.85 | PKM (0.62) | KMT2AMEN1ALDH1A1LMNAATM | |
| SCHEMBL6780775 | 0.84 | KMT2A (0.59) | KMT2AMEN1ALDH1A1LMNAATM | |
| SCHEMBL6954912 | 0.84 | KMT2A (0.58) | KMT2AMEN1ALDH1A1LMNAATM | |
| SCHEMBL6965642 | 0.83 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6966620 | 0.83 | KMT2A (0.60) | KMT2AMEN1ALDH1A1LMNAATM | |
| SCHEMBL6961415 | 0.83 | KMT2A (0.57) | KMT2AMEN1ALDH1A1LMNAATM | |
| SCHEMBL6780561 | 0.82 | MEN1 (0.73) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |
| EP-0850222-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 1998-07-01 | — | — | EP | disclosed |
| WO-1998000402-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1998-01-08 | — | — | WO | disclosed |