Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | GAK | O14976 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | YES1 | P07947 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963151 | 0.92 | HTR2A (0.35) | MAPTKMT2ATP53SMN1; SMN2NPSR1 | |
| SCHEMBL6957959 | 0.92 | SMN1; SMN2 (0.38) | MAPTKMT2ATP53SMN1; SMN2NPSR1 | |
| SCHEMBL6961241 | 0.91 | HTR2A (0.36) | MAPTKMT2ATP53SMN1; SMN2NPSR1 | |
| SCHEMBL6958506 | 0.91 | SMN1; SMN2 (0.39) | MAPTKMT2ATP53SMN1; SMN2NPSR1 | |
| SCHEMBL6962207 | 0.90 | SMN1; SMN2 (0.38) | KMT2ATP53SMN1; SMN2NPSR1SRC | |
| SCHEMBL6961412 | 0.90 | SMN1; SMN2 (0.37) | MAPTKMT2ATP53SMN1; SMN2NPSR1 | |
| SCHEMBL6957189 | 0.88 | SMN1; SMN2 (0.37) | MAPTKMT2ASMN1; SMN2NPSR1PPARA | |
| SCHEMBL6964622 | 0.88 | SMN1; SMN2 (0.37) | SMN1; SMN2NPSR1 | |
| SCHEMBL6962244 | 0.88 | KMT2A (0.35) | MAPTKMT2ATP53SMN1; SMN2NPSR1 | |
| SCHEMBL6959003 | 0.88 | TP53 (0.41) | MAPTKMT2ATP53SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | claimed |
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |