Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR1F | P30939 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | GALR2 | O43603 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957189 | 0.94 | SMN1; SMN2 (0.37) | SMN1; SMN2NPSR1SRD5A1SRD5A2HTR1A | |
| SCHEMBL6955562 | 0.93 | SRD5A1 (0.37) | SRD5A1SRD5A2APP | |
| SCHEMBL6958506 | 0.93 | SMN1; SMN2 (0.39) | SMN1; SMN2NPSR1SRD5A1SRD5A2HTR1A | |
| SCHEMBL6962207 | 0.91 | SMN1; SMN2 (0.38) | SMN1; SMN2NPSR1HTR1AHTR1DHTR1B | |
| SCHEMBL6961412 | 0.91 | SMN1; SMN2 (0.37) | SMN1; SMN2NPSR1SCN9A | |
| SCHEMBL6957959 | 0.90 | SMN1; SMN2 (0.38) | SMN1; SMN2NPSR1HTR1AHTR1DHTR1B | |
| SCHEMBL6959003 | 0.89 | TP53 (0.41) | SMN1; SMN2NPSR1SRD5A1SRD5A2 | |
| SCHEMBL6961033 | 0.88 | SRD5A1 (0.36) | SMN1; SMN2SRD5A1SRD5A2APP | |
| SCHEMBL6958365 | 0.88 | MAPT (0.38) | SMN1; SMN2NPSR1 | |
| SCHEMBL6958613 | 0.88 | MAPT (0.37) | SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | claimed |
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |