Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | DRD3 | P35462 | 8/20 | 0.42 |
| ▸ | DRD2 | P14416 | 7/20 | 0.42 |
| ▸ | DRD4 | P21917 | 6/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.41 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967112 | 0.85 | HTR2A (0.48) | HTR2ASLC6A4DRD3DRD2DRD4 | |
| SCHEMBL5500239 | 0.82 | HTR2A (0.47) | HTR2ASLC6A4DRD3DRD2DRD4 | |
| SCHEMBL7084849 | 0.81 | HTR2A (0.44) | HTR2ASLC6A4DRD3DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL6962899 | 0.81 | HTR2A (0.46) | HTR2ASLC6A4DRD3DRD2DRD4 | |
| SCHEMBL6964395 | 0.81 | CHRM1 (0.46) | HTR2ASLC6A4DRD3DRD2DRD4 | |
| SCHEMBL6962464 | 0.78 | SLC6A4 (0.46) | HTR2ASLC6A4DRD3DRD2DRD4 | |
| SCHEMBL6963416 | 0.74 | CHRM1 (0.58) | DRD3DRD2DRD4CHRM2CHRM1 | |
| SCHEMBL5498986 | 0.74 | HTR2A (0.51) | HTR2ASLC6A4DRD3DRD2DRD4 | |
| SCHEMBL6957807 | 0.73 | SLC6A1 (0.45) | HTR2ASLC6A4DRD3DRD2DRD4 | |
| SCHEMBL13051501 | 0.71 | HTR2A (0.78) | HTR2ASLC6A4DRD3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820451-B1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK AS (DK) | 2003-01-15 | — | — | EP | claimed |