Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.46 |
| ▸ | DRD3 | P35462 | 5/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | DRD1 | P21728 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7084849 | 0.90 | HTR2A (0.44) | HTR2AMTNR1AMTNR1BSLC6A4DRD3 | |
| SCHEMBL6958438 | 0.85 | HTR2A (0.44) | HTR2AMTNR1AMTNR1BSLC6A4DRD3 | |
| SCHEMBL6964395 | 0.84 | CHRM1 (0.46) | HTR2ASLC6A4DRD3SLC6A2CHRM2 | |
| SCHEMBL5498986 | 0.80 | HTR2A (0.51) | HTR2AMTNR1AMTNR1BSLC6A4DRD3 | |
| SCHEMBL6963416 | 0.78 | CHRM1 (0.58) | DRD3CHRM2CHRM1ADRA1ADRD2 | |
| SCHEMBL8202612 | 0.76 | SLC6A1 (0.61) | SLC6A4DRD3SLC6A2CHRM2CHRM1 | |
| SCHEMBL6968012 | 0.76 | SLC6A1 (0.50) | SLC6A4DRD3SLC6A2CHRM2CHRM1 | |
| SCHEMBL6957807 | 0.76 | SLC6A1 (0.45) | HTR2ASLC6A4DRD3SLC6A2CHRM2 | |
| SCHEMBL8206721 | 0.76 | SLC6A1 (0.61) | SLC6A4DRD3SLC6A2CHRM2CHRM1 | |
| SCHEMBL6968389 | 0.76 | SLC6A1 (0.49) | DRD3CHRM2CHRM1ADRA1ASLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820451-B1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK AS (DK) | 2003-01-15 | — | — | EP | claimed |